Large-scale production of lentiviral tools

Vectalys offers customised lentiviral vectors at a large-scale (>10 ml) in Vectalys Premium quality.

The popularity of lentiviral vectors in pre-clinical & clinical programs brings pharmaceutical companies to consider large volumes of vectors for their development projects. To meet these needs, Vectalys provides large-scale production of lentiviral tools and guarantees the same high quality whatever the volume.

High quality lentiviral manufacturing platform

Vectalys provides large-scale lentiviral vector productions (>10 ml) with the same titer, purity and lead time as small scale Vectalys Premium batches.

As a result, the same premium lentiviral vector composition can be used going from research to therapeutics:

Same high quality from small to large-scale lentiviral production

The data above exhibit the same viral product features and demonstrate our capability to produce the same high quality lentiviral vector batches from small to large-scale productions. The same quality of vector means a seamless scaling up from small to large cell number experiments.

Use the same quality from basic research to therapeutics

Large scale applications

Applications:

  • Pre-clinical gene therapy assays (CAR T cells, immunotherapy, gene editing, inherited genetic diseases)
  • Animal disease modelling (vaccination, metabolic disorder, other models…)
  • High throughput screening

Estimated number of transduction experiments you can expect with each volume:

Estimated number of transductions

The image above represents an estimated number of transductions one could perform with each scale of lentiviral vector batches, on HEK293T and T lymphocytes. For example, a single 25ml batch of highly purified and concentrated lentiviral vectors, allows to perform 5000 transductions of HEK293T cells into 6 well plates.

Any question about your project ? Please feel free to contact us at tech@vectalys.com.