Vectalys carry out the preliminary bibliographic and/or bioinformatic study of your gene expression or silencing project. Vectalys provide customized solutions, adapting to your specific needs:

• We help you to define and analyze target gene(s), and provide detailed gene study (alternative transcripts, homology, similarity search, expression pattern, SNP ...).
• If you are interested in gene silencing, we offer our know-how about shRNA. You can benefit from our in-house shRNA design pipeline, which takes into account thermodynamic parameters and target mRNA secondary structure in addition to usual efficacy and specificity criteria.
• We can also provide a specific assistance in order to define the expression cassette and the cloning strategy.
• If you don’t have the gene of interest, we can help you define the best strategy to obtain it and find the best source based on the bibliographic/bioinformatic gene expression pattern analysis.
• You can benefit from our expertise in the design of customized expression cassette: promoters, multicistronic and inducible systems, and different reporter genes.